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QSAR and molecular docking for the search of AOX inhibitors: a rational drug discovery approach

The alternative oxidase (AOX) is a monotopic diiron carboxylate protein that catalyses the oxidation of ubiquinol and the reduction of oxygen to water. Although a number of AOX inhibitors have been discovered, little is still known about the ligand–protein interaction and essential chemical characte...

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Detalles Bibliográficos
Autores principales:	Rosell-Hidalgo, Alicia, Young, Luke, Moore, Anthony L., Ghafourian, Taravat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904559/ https://www.ncbi.nlm.nih.gov/pubmed/33289903 http://dx.doi.org/10.1007/s10822-020-00360-8

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