Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler

Virtually all aspects of cell biology are regulated by a ubiquitin code where distinct ubiquitin chain architectures guide the binding events and itineraries of modified substrates. Various combinations of E2 and E3 enzymes accomplish chain formation by forging isopeptide bonds between the C-terminu...

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Detalles Bibliográficos
Autores principales: Liwocha, Joanna, Krist, David T., van der Heden van Noort, Gerbrand J., Hansen, Fynn M., Truong, Vinh H., Karayel, Ozge, Purser, Nicholas, Houston, Daniel, Burton, Nicole, Bostock, Mark J., Sattler, Michael, Mann, Matthias, Harrison, Joseph S., Kleiger, Gary, Ovaa, Huib, Schulman, Brenda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904580/
https://www.ncbi.nlm.nih.gov/pubmed/33288957
http://dx.doi.org/10.1038/s41589-020-00696-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904580/
https://www.ncbi.nlm.nih.gov/pubmed/33288957
http://dx.doi.org/10.1038/s41589-020-00696-0

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