Defects of full-length dystrophin trigger retinal neuron damage and synapse alterations by disrupting functional autophagy

Dystrophin (dys) mutations predispose Duchenne muscular disease (DMD) patients to brain and retinal complications. Although different dys variants, including long dys products, are expressed in the retina, their function is largely unknown. We investigated the putative role of full-length dystrophin...

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Detalles Bibliográficos
Autores principales: Catalani, Elisabetta, Bongiorni, Silvia, Taddei, Anna Rita, Mezzetti, Marta, Silvestri, Federica, Coazzoli, Marco, Zecchini, Silvia, Giovarelli, Matteo, Perrotta, Cristiana, De Palma, Clara, Clementi, Emilio, Ceci, Marcello, Prantera, Giorgio, Cervia, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904721/
https://www.ncbi.nlm.nih.gov/pubmed/32749504
http://dx.doi.org/10.1007/s00018-020-03598-5

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