Poly(ADP-ribosyl)ation enhances HuR oligomerization and contributes to pro-inflammatory gene mRNA stabilization

Poly(ADP-ribosyl)ation (PARylation) is an important post-translational modification mainly catalyzed by poly-ADP-ribose polymerase 1 (PARP1). In addition to having important roles in DNA damage detection and repair, it functions in gene expression regulation, especially at the posttranscriptional le...

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Detalles Bibliográficos
Autores principales: Ke, Yueshuang, Lv, Xueping, Fu, Xingyue, Zhang, Jing, Bohio, Ameer Ali, Zeng, Xianlu, Hao, Wenjing, Wang, Ruoxi, Boldogh, Istvan, Ba, Xueqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904744/
https://www.ncbi.nlm.nih.gov/pubmed/32789690
http://dx.doi.org/10.1007/s00018-020-03618-4

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