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Accurate imputation of human leukocyte antigens with CookHLA

The recent development of imputation methods enabled the prediction of human leukocyte antigen (HLA) alleles from intergenic SNP data, allowing studies to fine-map HLA for immune phenotypes. Here we report an accurate HLA imputation method, CookHLA, which has superior imputation accuracy compared to...

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Detalles Bibliográficos
Autores principales: Cook, Seungho, Choi, Wanson, Lim, Hyunjoon, Luo, Yang, Kim, Kunhee, Jia, Xiaoming, Raychaudhuri, Soumya, Han, Buhm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904773/
https://www.ncbi.nlm.nih.gov/pubmed/33627654
http://dx.doi.org/10.1038/s41467-021-21541-5