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Accurate imputation of human leukocyte antigens with CookHLA
The recent development of imputation methods enabled the prediction of human leukocyte antigen (HLA) alleles from intergenic SNP data, allowing studies to fine-map HLA for immune phenotypes. Here we report an accurate HLA imputation method, CookHLA, which has superior imputation accuracy compared to...
Autores principales: | Cook, Seungho, Choi, Wanson, Lim, Hyunjoon, Luo, Yang, Kim, Kunhee, Jia, Xiaoming, Raychaudhuri, Soumya, Han, Buhm |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904773/ https://www.ncbi.nlm.nih.gov/pubmed/33627654 http://dx.doi.org/10.1038/s41467-021-21541-5 |
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