Accelerating target deconvolution for therapeutic antibody candidates using highly parallelized genome editing

Therapeutic antibodies are transforming the treatment of cancer and autoimmune diseases. Today, a key challenge is finding antibodies against new targets. Phenotypic discovery promises to achieve this by enabling discovery of antibodies with therapeutic potential without specifying the molecular tar...

Descripción completa

Detalles Bibliográficos
Autores principales: Mattsson, Jenny, Ekdahl, Ludvig, Junghus, Fredrik, Ajore, Ram, Erlandsson, Eva, Niroula, Abhishek, Pertesi, Maroulio, Frendéus, Björn, Teige, Ingrid, Nilsson, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904777/
https://www.ncbi.nlm.nih.gov/pubmed/33627649
http://dx.doi.org/10.1038/s41467-021-21518-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904777/
https://www.ncbi.nlm.nih.gov/pubmed/33627649
http://dx.doi.org/10.1038/s41467-021-21518-4

Ejemplares similares