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Accelerating target deconvolution for therapeutic antibody candidates using highly parallelized genome editing
Therapeutic antibodies are transforming the treatment of cancer and autoimmune diseases. Today, a key challenge is finding antibodies against new targets. Phenotypic discovery promises to achieve this by enabling discovery of antibodies with therapeutic potential without specifying the molecular tar...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904777/ https://www.ncbi.nlm.nih.gov/pubmed/33627649 http://dx.doi.org/10.1038/s41467-021-21518-4 |