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Siplizumab Induces NK Cell Fratricide Through Antibody-Dependent Cell-Mediated Cytotoxicity

The glycoprotein CD2 is expressed on T and NK cells and contributes to cell-cell conjugation, agonistic signaling and actin cytoskeleton rearrangement. CD2 has previously been shown to have an important function in natural NK cell cytotoxicity but to be expendable in antibody-mediated cytotoxicity....

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Detalles Bibliográficos
Autores principales:	Binder, Christian, Sellberg, Felix, Cvetkovski, Filip, Berg, Stefan, Berglund, Erik, Berglund, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904868/ https://www.ncbi.nlm.nih.gov/pubmed/33643309 http://dx.doi.org/10.3389/fimmu.2021.599526

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