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Discovery of exolytic heparinases and their catalytic mechanism and potential application

Heparinases (Hepases) are critical tools for the studies of highly heterogeneous heparin (HP)/heparan sulfate (HS). However, exolytic heparinases urgently needed for the sequencing of HP/HS chains remain undiscovered. Herein, a type of exolytic heparinases (exoHepases) is identified from the genomes...

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Detalles Bibliográficos
Autores principales: Zhang, Qingdong, Cao, Hai-Yan, Wei, Lin, Lu, Danrong, Du, Min, Yuan, Min, Shi, Deling, Chen, Xiangxue, Wang, Peng, Chen, Xiu-Lan, Chi, Lianli, Zhang, Yu-Zhong, Li, Fuchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904915/
https://www.ncbi.nlm.nih.gov/pubmed/33627653
http://dx.doi.org/10.1038/s41467-021-21441-8

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