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Neuroticism alters the transcriptome of the frontal cortex to contribute to the cognitive decline and onset of Alzheimer’s disease

Accumulating evidence has suggested that the molecular transcriptional mechanism contributes to Alzheimer’s disease (AD) and its endophenotypes of cognitive decline and neuropathological traits, β-amyloid (Aβ) and phosphorylated tangles (TAU). However, it is unknown what is the impact of the AD risk...

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Detalles Bibliográficos
Autores principales: De Jager, Céline H., White, Charles C., Bennett, David A., Ma, Yiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904919/
https://www.ncbi.nlm.nih.gov/pubmed/33627625
http://dx.doi.org/10.1038/s41398-021-01253-6