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Optogenetic current in myofibroblasts acutely alters electrophysiology and conduction of co-cultured cardiomyocytes
Interactions between cardiac myofibroblasts and myocytes may slow conduction and generate spontaneous beating in fibrosis, increasing the chance of life-threatening arrhythmia. While co-culture studies have shown that myofibroblasts can affect cardiomyocyte electrophysiology in vitro, the extent of ...
Autores principales: | Kostecki, Geran M., Shi, Yu, Chen, Christopher S., Reich, Daniel H., Entcheva, Emilia, Tung, Leslie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904933/ https://www.ncbi.nlm.nih.gov/pubmed/33627695 http://dx.doi.org/10.1038/s41598-021-83398-4 |
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