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Fibrogranular materials function as organizers to ensure the fidelity of multiciliary assembly

Multicilia are delicate motile machineries, and how they are accurately assembled is poorly understood. Here, we show that fibrogranular materials (FGMs), large arrays of electron-dense granules specific to multiciliated cells, are essential for their ultrastructural fidelity. Pcm1 forms the granula...

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Detalles Bibliográficos
Autores principales:	Zhao, Huijie, Chen, Qingxia, Li, Fan, Cui, Lihong, Xie, Lele, Huang, Qiongping, Liang, Xin, Zhou, Jun, Yan, Xiumin, Zhu, Xueliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904937/ https://www.ncbi.nlm.nih.gov/pubmed/33627667 http://dx.doi.org/10.1038/s41467-021-21506-8

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