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Prediction of drug–target binding affinity using similarity-based convolutional neural network

Identifying novel drug–target interactions (DTIs) plays an important role in drug discovery. Most of the computational methods developed for predicting DTIs use binary classification, whose goal is to determine whether or not a drug–target (DT) pair interacts. However, it is more meaningful but also...

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Detalles Bibliográficos
Autores principales:	Shim, Jooyong, Hong, Zhen-Yu, Sohn, Insuk, Hwang, Changha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904939/ https://www.ncbi.nlm.nih.gov/pubmed/33627791 http://dx.doi.org/10.1038/s41598-021-83679-y

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