βA1-crystallin regulates glucose metabolism and mitochondrial function in mouse retinal astrocytes by modulating PTP1B activity

βA3/A1-crystallin, a lens protein that is also expressed in astrocytes, is produced as βA3 and βA1-crystallin isoforms by leaky ribosomal scanning. In a previous human proteome high-throughput array, we found that βA3/A1-crystallin interacts with protein tyrosine phosphatase 1B (PTP1B), a key regula...

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Detalles Bibliográficos
Autores principales: Ghosh, Sayan, Liu, Haitao, Yazdankhah, Meysam, Stepicheva, Nadezda, Shang, Peng, Vaidya, Tanuja, Hose, Stacey, Gupta, Urvi, Calderon, Michael Joseph, Hu, Ming-Wen, Nair, Archana Padmanabhan, Weiss, Joseph, Fitting, Christopher S., Bhutto, Imran A., Gadde, Santosh Gopi Krishna, Naik, Naveen Kumar, Jaydev, Chaitra, Lutty, Gerard A., Handa, James T., Jayagopal, Ashwath, Qian, Jiang, Sahel, José-Alain, Rajasundaram, Dhivyaa, Sergeev, Yuri, Zigler, J. Samuel, Sethu, Swaminathan, Watkins, Simon, Ghosh, Arkasubhra, Sinha, Debasish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7904954/
https://www.ncbi.nlm.nih.gov/pubmed/33627831
http://dx.doi.org/10.1038/s42003-021-01763-5

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