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Ccn6 Is Required for Mitochondrial Integrity and Skeletal Muscle Function in Zebrafish

Mutations in the CCN6 (WISP3) gene are linked with a debilitating musculoskeletal disorder, termed progressive pseudorheumatoid dysplasia (PPRD). Yet, the functional significance of CCN6 in the musculoskeletal system remains unclear. Using zebrafish as a model organism, we demonstrated that zebrafis...

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Detalles Bibliográficos
Autores principales: Sengupta, Archya, Padhan, Deepesh Kumar, Ganguly, Ananya, Sen, Malini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905066/
https://www.ncbi.nlm.nih.gov/pubmed/33644064
http://dx.doi.org/10.3389/fcell.2021.627409