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Targeting POLE2 Creates a Novel Vulnerability in Renal Cell Carcinoma via Modulating Stanniocalcin 1

OBJECTIVE: The aim of this study is to investigate the biological functions and the underlying mechanisms of DNA polymerase epsilon subunit 2 (POLE2) in renal cell carcinoma (RCC). METHODS: The datasets of POLE2 expression in The Cancer Genome Atlas Kidney Clear Cell Carcinoma (TCGA-KIRC) and Intern...

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Detalles Bibliográficos
Autores principales:	Zhang, Chuanjie, Shen, Yan, Gao, Lili, Wang, Xiaojing, Huang, Da, Xie, Xin, Xu, Danfeng, He, Hongchao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905105/ https://www.ncbi.nlm.nih.gov/pubmed/33644060 http://dx.doi.org/10.3389/fcell.2021.622344

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