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Advances in the Treatment of Anal Fistula: A Mini-Review of Recent Five-Year Clinical Studies
Anal fistula, with its complicated pathogenesis, has been considered as a clinical challenge for centuries. The risk of frequent recurrence and incontinence constitutes a considerable threat in the long-term treatment of anal fistula. In this work, we narratively reviewed the scientific literature o...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905164/ https://www.ncbi.nlm.nih.gov/pubmed/33644110 http://dx.doi.org/10.3389/fsurg.2020.586891 |
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author | Ji, Lijiang Zhang, Yang Xu, Liang Wei, Jun Weng, Liping Jiang, Jie |
author_facet | Ji, Lijiang Zhang, Yang Xu, Liang Wei, Jun Weng, Liping Jiang, Jie |
author_sort | Ji, Lijiang |
collection | PubMed |
description | Anal fistula, with its complicated pathogenesis, has been considered as a clinical challenge for centuries. The risk of frequent recurrence and incontinence constitutes a considerable threat in the long-term treatment of anal fistula. In this work, we narratively reviewed the scientific literature of new techniques that have been used for anal fistula treatment over the recent 5 years, objectively evaluated the pros and cons of each technique on the basis of clinical outcomes, and tried to disclose the effective strategies for anal fistula treatment. Up to date, surgery is the main method used for treating anal fistula, but there is no simple technique that can completely heal complex anal fistula. In the course of surgery treatment, the healing outcome, and the protection of anal function should be weighed comprehensively. Among the innovative techniques that have emerged in recent years, combined techniques based on drainage Seton and LIFT-plug seem to be the relatively effective therapies, but their effectiveness requires more multi-center prospective randomized controlled trials with large sample size and long-term follow-up to be validated. |
format | Online Article Text |
id | pubmed-7905164 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-79051642021-02-26 Advances in the Treatment of Anal Fistula: A Mini-Review of Recent Five-Year Clinical Studies Ji, Lijiang Zhang, Yang Xu, Liang Wei, Jun Weng, Liping Jiang, Jie Front Surg Surgery Anal fistula, with its complicated pathogenesis, has been considered as a clinical challenge for centuries. The risk of frequent recurrence and incontinence constitutes a considerable threat in the long-term treatment of anal fistula. In this work, we narratively reviewed the scientific literature of new techniques that have been used for anal fistula treatment over the recent 5 years, objectively evaluated the pros and cons of each technique on the basis of clinical outcomes, and tried to disclose the effective strategies for anal fistula treatment. Up to date, surgery is the main method used for treating anal fistula, but there is no simple technique that can completely heal complex anal fistula. In the course of surgery treatment, the healing outcome, and the protection of anal function should be weighed comprehensively. Among the innovative techniques that have emerged in recent years, combined techniques based on drainage Seton and LIFT-plug seem to be the relatively effective therapies, but their effectiveness requires more multi-center prospective randomized controlled trials with large sample size and long-term follow-up to be validated. Frontiers Media S.A. 2021-02-11 /pmc/articles/PMC7905164/ /pubmed/33644110 http://dx.doi.org/10.3389/fsurg.2020.586891 Text en Copyright © 2021 Ji, Zhang, Xu, Wei, Weng and Jiang. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Surgery Ji, Lijiang Zhang, Yang Xu, Liang Wei, Jun Weng, Liping Jiang, Jie Advances in the Treatment of Anal Fistula: A Mini-Review of Recent Five-Year Clinical Studies |
title | Advances in the Treatment of Anal Fistula: A Mini-Review of Recent Five-Year Clinical Studies |
title_full | Advances in the Treatment of Anal Fistula: A Mini-Review of Recent Five-Year Clinical Studies |
title_fullStr | Advances in the Treatment of Anal Fistula: A Mini-Review of Recent Five-Year Clinical Studies |
title_full_unstemmed | Advances in the Treatment of Anal Fistula: A Mini-Review of Recent Five-Year Clinical Studies |
title_short | Advances in the Treatment of Anal Fistula: A Mini-Review of Recent Five-Year Clinical Studies |
title_sort | advances in the treatment of anal fistula: a mini-review of recent five-year clinical studies |
topic | Surgery |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905164/ https://www.ncbi.nlm.nih.gov/pubmed/33644110 http://dx.doi.org/10.3389/fsurg.2020.586891 |
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