(18)F-Fluorodeoxyglucose Positron Emission Tomography–Computed Tomography in Malignant Transformation of Paget's Disease of Bone

Malignant transformation Paget's disease of bone to sarcoma is relatively rare, occurring in approximately 1% of these patients. Although few clinical and imaging findings may help in prediction of malignant transformation, most of them are nonspecific. We describe a case of carcinoma vocal cor...

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Detalles Bibliográficos
Autores principales: Senthil, Raja, Gangadharan, Vadavattathu Padmanabhan, Ramachandran Nair, Arun Visakh, Mahadevan, Pushpa, Pratap, Thara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905288/
https://www.ncbi.nlm.nih.gov/pubmed/33642771
http://dx.doi.org/10.4103/ijnm.IJNM_99_20
Descripción
Sumario:Malignant transformation Paget's disease of bone to sarcoma is relatively rare, occurring in approximately 1% of these patients. Although few clinical and imaging findings may help in prediction of malignant transformation, most of them are nonspecific. We describe a case of carcinoma vocal cord and Paget's disease of bone with sarcomatous transformation, where (18)F-fluorodeoxyglucose (FDG) positron emission tomography–computed tomography was helpful in accurate diagnosis by demonstrating differential intense FDG uptake in transformed areas of pagetic bone and also FDG-avid osteoblastic pulmonary metastasis.

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