(18)F-Fluorodeoxyglucose Positron Emission Tomography–Computed Tomography in Malignant Transformation of Paget's Disease of Bone

Malignant transformation Paget's disease of bone to sarcoma is relatively rare, occurring in approximately 1% of these patients. Although few clinical and imaging findings may help in prediction of malignant transformation, most of them are nonspecific. We describe a case of carcinoma vocal cor...

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Autores principales: Senthil, Raja, Gangadharan, Vadavattathu Padmanabhan, Ramachandran Nair, Arun Visakh, Mahadevan, Pushpa, Pratap, Thara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Interesting Image
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905288/
https://www.ncbi.nlm.nih.gov/pubmed/33642771
http://dx.doi.org/10.4103/ijnm.IJNM_99_20
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author Senthil, Raja
Gangadharan, Vadavattathu Padmanabhan
Ramachandran Nair, Arun Visakh
Mahadevan, Pushpa
Pratap, Thara
author_facet Senthil, Raja
Gangadharan, Vadavattathu Padmanabhan
Ramachandran Nair, Arun Visakh
Mahadevan, Pushpa
Pratap, Thara
author_sort Senthil, Raja
collection PubMed
description Malignant transformation Paget's disease of bone to sarcoma is relatively rare, occurring in approximately 1% of these patients. Although few clinical and imaging findings may help in prediction of malignant transformation, most of them are nonspecific. We describe a case of carcinoma vocal cord and Paget's disease of bone with sarcomatous transformation, where (18)F-fluorodeoxyglucose (FDG) positron emission tomography–computed tomography was helpful in accurate diagnosis by demonstrating differential intense FDG uptake in transformed areas of pagetic bone and also FDG-avid osteoblastic pulmonary metastasis.
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spelling pubmed-79052882021-02-26 (18)F-Fluorodeoxyglucose Positron Emission Tomography–Computed Tomography in Malignant Transformation of Paget's Disease of Bone Senthil, Raja Gangadharan, Vadavattathu Padmanabhan Ramachandran Nair, Arun Visakh Mahadevan, Pushpa Pratap, Thara Indian J Nucl Med Interesting Image Malignant transformation Paget's disease of bone to sarcoma is relatively rare, occurring in approximately 1% of these patients. Although few clinical and imaging findings may help in prediction of malignant transformation, most of them are nonspecific. We describe a case of carcinoma vocal cord and Paget's disease of bone with sarcomatous transformation, where (18)F-fluorodeoxyglucose (FDG) positron emission tomography–computed tomography was helpful in accurate diagnosis by demonstrating differential intense FDG uptake in transformed areas of pagetic bone and also FDG-avid osteoblastic pulmonary metastasis. Wolters Kluwer - Medknow 2020 2020-10-21 /pmc/articles/PMC7905288/ /pubmed/33642771 http://dx.doi.org/10.4103/ijnm.IJNM_99_20 Text en Copyright: © 2020 Indian Journal of Nuclear Medicine http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Interesting Image
Senthil, Raja
Gangadharan, Vadavattathu Padmanabhan
Ramachandran Nair, Arun Visakh
Mahadevan, Pushpa
Pratap, Thara
(18)F-Fluorodeoxyglucose Positron Emission Tomography–Computed Tomography in Malignant Transformation of Paget's Disease of Bone
title (18)F-Fluorodeoxyglucose Positron Emission Tomography–Computed Tomography in Malignant Transformation of Paget's Disease of Bone
title_full (18)F-Fluorodeoxyglucose Positron Emission Tomography–Computed Tomography in Malignant Transformation of Paget's Disease of Bone
title_fullStr (18)F-Fluorodeoxyglucose Positron Emission Tomography–Computed Tomography in Malignant Transformation of Paget's Disease of Bone
title_full_unstemmed (18)F-Fluorodeoxyglucose Positron Emission Tomography–Computed Tomography in Malignant Transformation of Paget's Disease of Bone
title_short (18)F-Fluorodeoxyglucose Positron Emission Tomography–Computed Tomography in Malignant Transformation of Paget's Disease of Bone
title_sort (18)f-fluorodeoxyglucose positron emission tomography–computed tomography in malignant transformation of paget's disease of bone
topic Interesting Image
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905288/
https://www.ncbi.nlm.nih.gov/pubmed/33642771
http://dx.doi.org/10.4103/ijnm.IJNM_99_20
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