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CART mitigates oxidative stress and DNA damage in memory deficits of APP/PS1 mice via upregulating β-amyloid metabolism-associated enzymes

Alzheimer's disease (AD) is the most common form of dementia that is primarily characterized by progressive cognitive deficits. The toxicity of amyloid β-protein (Aβ) serves an important role in the progression of AD, resulting in neuronal loss via a number of possible mechanisms, including oxi...

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Detalles Bibliográficos
Autores principales: Jiang, Hui, Niu, Fengnan, Zheng, Yan, Xu, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905330/
https://www.ncbi.nlm.nih.gov/pubmed/33604684
http://dx.doi.org/10.3892/mmr.2021.11919