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Biomarkers of Checkpoint Inhibitor Induced Immune-Related Adverse Events—A Comprehensive Review

Immune checkpoint inhibitors (ICIs) have substantially improved the prognosis of patients with different types of cancer. Through blockade of cytotoxic T-lymphocyte antigen 4 (CTLA-4) and programmed cell death protein 1 (PD-1), negative feedback mechanisms of the immune system are inhibited, potenti...

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Detalles Bibliográficos
Autores principales: Hommes, Josefien W., Verheijden, Rik J., Suijkerbuijk, Karijn P. M., Hamann, Dörte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905347/
https://www.ncbi.nlm.nih.gov/pubmed/33643899
http://dx.doi.org/10.3389/fonc.2020.585311