Optimized protocol for an inducible rat model of liver tumor with chronic hepatocellular injury, inflammation, fibrosis, and cirrhosis

Animal models of liver cancer are instrumental in the study of hepatocarcinogenesis and development of novel therapeutic approaches. Here, we describe steps to establish liver cancer in a rat model, via chronic administration of diethylnitrosamine. This causes liver tumors with a sequential progress...

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Detalles Bibliográficos
Autores principales: Chen, Zhiao, Li, Shengli, Han, Leng, He, Xianghuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905469/
https://www.ncbi.nlm.nih.gov/pubmed/33665633
http://dx.doi.org/10.1016/j.xpro.2021.100353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905469/
https://www.ncbi.nlm.nih.gov/pubmed/33665633
http://dx.doi.org/10.1016/j.xpro.2021.100353

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