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GLP-1 improves the supportive ability of astrocytes to neurons by promoting aerobic glycolysis in Alzheimer's disease
OBJECTIVE: Astrocytes actively participate in energy metabolism in the brain, and astrocytic aerobic glycolysis disorder is associated with the pathology of Alzheimer's disease (AD). GLP-1 has been shown to improve cognition in AD; however, the mechanism remains unclear. The objectives of this...
Autores principales: | Zheng, Jiaping, Xie, Yunzhen, Ren, Lingjia, Qi, Liqin, Wu, Li, Pan, Xiaodong, Zhou, Jianxing, Chen, Zhou, Liu, Libin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905479/ https://www.ncbi.nlm.nih.gov/pubmed/33556642 http://dx.doi.org/10.1016/j.molmet.2021.101180 |
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