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In vivo, ex vivo and in vitro dasatinib activity in chronic lymphocytic leukemia

Dasatinib inhibits the breakpoint cluster region-Abelson murine leukemia 1 (BCR-ABL1) gene along with other kinases known to be overexpressed and abnormally active in patients with chronic lymphocytic leukemia (CLL). The current study used primary leukemic cells obtained from 53 patients with CLL th...

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Detalles Bibliográficos
Autores principales: Giannopoulos, Krzysztof, Karczmarczyk, Agnieszka, Karp, Marta, Bojarska-Junak, Agnieszka, Kosior, Kamila, Kowal, Małgorzata, Tomczak, Waldemar, Hus, Marek, Machnicki, Marcin, Stokłosa, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905539/
https://www.ncbi.nlm.nih.gov/pubmed/33732361
http://dx.doi.org/10.3892/ol.2021.12546

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