Inflammasome activation controlled by the interplay between post-translational modifications: emerging drug target opportunities

Controlling the activation of the NLRP3 inflammasome by post-translational modifications (PTMs) of critical protein subunits has emerged as a key determinant in inflammatory processes as well as in pathophysiology. In this review, we put into context the kinases, ubiquitin processing and other PTM e...

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Detalles Bibliográficos
Autores principales: Liang, Zhu, Damianou, Andreas, Di Daniel, Elena, Kessler, Benedikt M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905589/
https://www.ncbi.nlm.nih.gov/pubmed/33627128
http://dx.doi.org/10.1186/s12964-020-00688-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905589/
https://www.ncbi.nlm.nih.gov/pubmed/33627128
http://dx.doi.org/10.1186/s12964-020-00688-6

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