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Inflammasome activation controlled by the interplay between post-translational modifications: emerging drug target opportunities
Controlling the activation of the NLRP3 inflammasome by post-translational modifications (PTMs) of critical protein subunits has emerged as a key determinant in inflammatory processes as well as in pathophysiology. In this review, we put into context the kinases, ubiquitin processing and other PTM e...
Autores principales: | Liang, Zhu, Damianou, Andreas, Di Daniel, Elena, Kessler, Benedikt M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905589/ https://www.ncbi.nlm.nih.gov/pubmed/33627128 http://dx.doi.org/10.1186/s12964-020-00688-6 |
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