Simvastatin impairs hippocampal synaptic plasticity and cognitive function in mice

Lipophilic statins which are blood brain barrier (BBB) permeable are speculated to affect the cholesterol synthesis and neural functions in the central nervous system. However, whether these statins can affect cholesterol levels and synaptic plasticity in hippocampus and the in vivo consequence rema...

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Detalles Bibliográficos
Autores principales: Guo, Yujun, Zou, Guichang, Qi, Keke, Jin, Jin, Yao, Lei, Pan, Yang, Xiong, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905661/
https://www.ncbi.nlm.nih.gov/pubmed/33627175
http://dx.doi.org/10.1186/s13041-021-00758-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905661/
https://www.ncbi.nlm.nih.gov/pubmed/33627175
http://dx.doi.org/10.1186/s13041-021-00758-x

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