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Penalized partial least squares for pleiotropy
BACKGROUND: The increasing number of genome-wide association studies (GWAS) has revealed several loci that are associated to multiple distinct phenotypes, suggesting the existence of pleiotropic effects. Highlighting these cross-phenotype genetic associations could help to identify and understand co...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905667/ https://www.ncbi.nlm.nih.gov/pubmed/33627076 http://dx.doi.org/10.1186/s12859-021-03968-1 |