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Penalized partial least squares for pleiotropy

BACKGROUND: The increasing number of genome-wide association studies (GWAS) has revealed several loci that are associated to multiple distinct phenotypes, suggesting the existence of pleiotropic effects. Highlighting these cross-phenotype genetic associations could help to identify and understand co...

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Detalles Bibliográficos
Autores principales: Broc, Camilo, Truong, Therese, Liquet, Benoit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905667/
https://www.ncbi.nlm.nih.gov/pubmed/33627076
http://dx.doi.org/10.1186/s12859-021-03968-1

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