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Anemia and Iron-Deficiency Anemia in Children Born to Mothers with HIV in Western Kenya
The objective of this study was to determine and compare anemia and iron-deficiency anemia (IDA) rates in young Kenyan children who are HIV infected (HI), HIV exposed, uninfected (HEU), and HIV unexposed (HU). Questionnaires, anthropometrics, and blood samples were collected from HI, HEU, and HU age...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905722/ https://www.ncbi.nlm.nih.gov/pubmed/33748341 http://dx.doi.org/10.1177/2333794X21991035 |
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author | Oyungu, Eren Roose, Anna W. Ombitsa, Ananda R. Yang, Ziyi Vreeman, Rachel C. McHenry, Megan S. |
author_facet | Oyungu, Eren Roose, Anna W. Ombitsa, Ananda R. Yang, Ziyi Vreeman, Rachel C. McHenry, Megan S. |
author_sort | Oyungu, Eren |
collection | PubMed |
description | The objective of this study was to determine and compare anemia and iron-deficiency anemia (IDA) rates in young Kenyan children who are HIV infected (HI), HIV exposed, uninfected (HEU), and HIV unexposed (HU). Questionnaires, anthropometrics, and blood samples were collected from HI, HEU, and HU aged 18 to 36 months. Descriptive statistics, Fisher’s exact tests, and linear regression were used for analysis. Of 137 total participants, HI (n = 18), HEU (n = 70), and HU (n = 49), 61.1%, 53.6%, and 36.7%, respectively, were anemic, with mean hemoglobin levels highest in HU (P = .006). After adjusting for covariates, HI (β = −9.6, 95% CI:−17.3 to −2.0) and HEU (β = −7.4, 95% CI: −12.9 to −1.9) had lower hemoglobin levels compared with HU. The proportion of children with IDA did not differ significantly across groups (P = .08). HEU have rates of anemia and IDA similar to HI. Anemia risk is generally higher in HEU than HU, even after adjusting for covariates. |
format | Online Article Text |
id | pubmed-7905722 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-79057222021-03-18 Anemia and Iron-Deficiency Anemia in Children Born to Mothers with HIV in Western Kenya Oyungu, Eren Roose, Anna W. Ombitsa, Ananda R. Yang, Ziyi Vreeman, Rachel C. McHenry, Megan S. Glob Pediatr Health Original Article The objective of this study was to determine and compare anemia and iron-deficiency anemia (IDA) rates in young Kenyan children who are HIV infected (HI), HIV exposed, uninfected (HEU), and HIV unexposed (HU). Questionnaires, anthropometrics, and blood samples were collected from HI, HEU, and HU aged 18 to 36 months. Descriptive statistics, Fisher’s exact tests, and linear regression were used for analysis. Of 137 total participants, HI (n = 18), HEU (n = 70), and HU (n = 49), 61.1%, 53.6%, and 36.7%, respectively, were anemic, with mean hemoglobin levels highest in HU (P = .006). After adjusting for covariates, HI (β = −9.6, 95% CI:−17.3 to −2.0) and HEU (β = −7.4, 95% CI: −12.9 to −1.9) had lower hemoglobin levels compared with HU. The proportion of children with IDA did not differ significantly across groups (P = .08). HEU have rates of anemia and IDA similar to HI. Anemia risk is generally higher in HEU than HU, even after adjusting for covariates. SAGE Publications 2021-02-22 /pmc/articles/PMC7905722/ /pubmed/33748341 http://dx.doi.org/10.1177/2333794X21991035 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Article Oyungu, Eren Roose, Anna W. Ombitsa, Ananda R. Yang, Ziyi Vreeman, Rachel C. McHenry, Megan S. Anemia and Iron-Deficiency Anemia in Children Born to Mothers with HIV in Western Kenya |
title | Anemia and Iron-Deficiency Anemia in Children Born to Mothers with HIV in Western Kenya |
title_full | Anemia and Iron-Deficiency Anemia in Children Born to Mothers with HIV in Western Kenya |
title_fullStr | Anemia and Iron-Deficiency Anemia in Children Born to Mothers with HIV in Western Kenya |
title_full_unstemmed | Anemia and Iron-Deficiency Anemia in Children Born to Mothers with HIV in Western Kenya |
title_short | Anemia and Iron-Deficiency Anemia in Children Born to Mothers with HIV in Western Kenya |
title_sort | anemia and iron-deficiency anemia in children born to mothers with hiv in western kenya |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905722/ https://www.ncbi.nlm.nih.gov/pubmed/33748341 http://dx.doi.org/10.1177/2333794X21991035 |
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