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Testing Possible Risk Factors for Idiosyncratic Drug-Induced Liver Injury Using an Amodiaquine Mouse Model and Co-treatment with 1-Methyl-d-Tryptophan or Acetaminophen

[Image: see text] Idiosyncratic drug reactions are unpredictable adverse reactions. Although most such adverse reactions appear to be immune mediated, their exact mechanism(s) remain elusive. The idiosyncratic drug reaction most associated with serious consequences is idiosyncratic drug-induced live...

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Detalles Bibliográficos
Autores principales: Cho, Tiffany, Kok, Lie Yun, Uetrecht, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905801/
https://www.ncbi.nlm.nih.gov/pubmed/33644572
http://dx.doi.org/10.1021/acsomega.0c05352