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Blockage of AMPK-ULK1 pathway mediated autophagy promotes cell apoptosis to increase doxorubicin sensitivity in breast cancer (BC) cells: an in vitro study

BACKGROUND: Activation of autophagy flux contributed to resistance of breast cancer (BC) cells to current chemotherapeutic drugs, which seriously limited their therapeutic efficacy and facilitated BC recurrence in clinic. However, the detailed mechanisms are still not fully understood. In the presen...

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Detalles Bibliográficos
Autores principales:	Yu, Libo, Shi, Qingtao, Jin, Yan, Liu, Zhixin, Li, Jiaxin, Sun, Wenzhou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7905888/ https://www.ncbi.nlm.nih.gov/pubmed/33632157 http://dx.doi.org/10.1186/s12885-021-07901-w

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