Cargando…

Dexrazoxane ameliorates radiation-induced heart disease in a rat model

Treatment of thoracic tumors with radiotherapy can lead to severe cardiac injury. We investigated the effects of dexrazoxane, a USFDA-approved cardioprotective drug administered with chemotherapy, on radiation-induced heart disease (RIHD) in a rat model. Male Sprague-Dawley rats were irradiated with...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Long, Nie, Xiaoqi, Zhang, Peng, Huang, Yongbiao, Ma, Li, Li, Fang, Yi, Minxiao, Qin, Wan, Yuan, Xianglin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906151/ https://www.ncbi.nlm.nih.gov/pubmed/33406500 http://dx.doi.org/10.18632/aging.202332

Ejemplares similares

Aerosolized Thyroid Hormone Prevents Radiation Induced Lung Fibrosis
por: Li, Long, et al.
Publicado: (2020)

Kinsenoside Protects Against Radiation-Induced Liver Fibrosis via Downregulating Connective Tissue Growth Factor Through TGF-β1 Signaling
por: Nie, Xiaoqi, et al.
Publicado: (2022)

Protective Effects of Dexrazoxane against Doxorubicin-Induced Cardiotoxicity: A Metabolomic Study
por: QuanJun, Yang, et al.
Publicado: (2017)

Anthracycline extravasation injuries: management with dexrazoxane
por: Jordan, Karin, et al.
Publicado: (2009)

Scavenging Effects of Dexrazoxane on Free Radicals
por: Junjing, Zhang, et al.
Publicado: (2010)

Irradiated Human Umbilical Vein Endothelial Cells Undergo Endothelial-Mesenchymal Transition via the Snail/miR-199a-5p Axis to Promote the Differentiation of Fibroblasts into Myofibroblasts
por: Yi, Minxiao, et al.
Publicado: (2018)

Dexrazoxane for the treatment of chemotherapy-related side effects
por: Langer, Seppo W
Publicado: (2014)

Effect of Dexrazoxane and Amifostine on the Vertebral Bone Quality of Doxorubicin Treated Male Rats
por: Mwale, F, et al.
Publicado: (2008)

A Novel Prognostic Signature for Survival Prediction and Immune Implication Based on SARS-CoV-2–Related Genes in Kidney Renal Clear Cell Carcinoma
por: Huang, Yongbiao, et al.
Publicado: (2022)

A Novel RNA Binding Protein-Related Prognostic Signature for Hepatocellular Carcinoma
por: Huang, Yongbiao, et al.
Publicado: (2020)

Dexrazoxane for Preventing Anthracycline Cardiotoxicity in Children with Solid Tumors
por: Choi, Hyoung Soo, et al.
Publicado: (2010)

Dexrazoxane for cardioprotection in older adults with acute myeloid leukemia
por: Vachhani, Pankit, et al.
Publicado: (2017)

Cisplatin/dexrazoxane/doxorubicin: Neutropenia and thrombocytopenia: case report
Publicado: (2020)

Efficacy of Dexrazoxane in Preventing Anthracycline Cardiotoxicity in Breast Cancer
por: Macedo, Ariane V.S., et al.
Publicado: (2019)

Exploring the Prognostic Value, Immune Implication and Biological Function of H2AFY Gene in Hepatocellular Carcinoma
por: Huang, Yongbiao, et al.
Publicado: (2021)

Development and Validation of New RP-HPLC Method for the Determination of Dexrazoxane
por: Basaveswara Rao, M. V., et al.
Publicado: (2012)

Dexrazoxane preferentially mitigates doxorubicin cardiotoxicity in female children with sarcoma
por: Narayan, Hari K, et al.
Publicado: (2019)

Efficacy of Dexrazoxane in Cardiac Protection in Pediatric Patients Treated With Anthracyclines
por: Rahimi, Parya, et al.
Publicado: (2023)

Induction of thrombospondin-1 partially mediates the anti-angiogenic activity of dexrazoxane
por: Maloney, S L, et al.
Publicado: (2009)

Dexrazoxane does not mitigate early vascular toxicity induced by doxorubicin in mice
por: Bosman, Matthias, et al.
Publicado: (2023)

Genetic variants in the plasminogen activator inhibitor‐1 gene are associated with an increased risk of radiation pneumonitis in lung cancer patients
por: Liu, Bo, et al.
Publicado: (2017)

Integrative Analysis Constructs an Extracellular Matrix-Associated Gene Signature for the Prediction of Survival and Tumor Immunity in Lung Adenocarcinoma
por: Xiao, Lingyan, et al.
Publicado: (2022)

Utility of Dexrazoxane for the Attenuation of Epirubicin-Induced Genetic Alterations in Mouse Germ Cells
por: Attia, Sabry M., et al.
Publicado: (2016)

Risk Factor Analysis for Secondary Malignancy in Dexrazoxane-Treated Pediatric Cancer Patients
por: Kim, Hyery, et al.
Publicado: (2019)

Canagliflozin mitigates ferroptosis and ameliorates heart failure in rats with preserved ejection fraction
por: Ma, Sai, et al.
Publicado: (2022)

Dexrazoxane Protects Cardiomyocyte from Doxorubicin-Induced Apoptosis by Modulating miR-17-5p
por: Yu, Xiaoxue, et al.
Publicado: (2020)

MMP-1 promoter polymorphism is associated with risk of radiation-induced lung injury in lung cancer patients treated with radiotherapy
por: Liu, Bo, et al.
Publicado: (2016)

Dexrazoxane significantly impairs the induction of doxorubicin resistance in the human leukaemia line, K562
por: Sargent, J M, et al.
Publicado: (2001)

Correction: Utility of Dexrazoxane for the Attenuation of Epirubicin-Induced Genetic Alterations in Mouse Germ Cells
por: Attia, Sabry M., et al.
Publicado: (2016)

Dexrazoxane Shows No Protective Effect in the Acute Phase of Reperfusion during Myocardial Infarction in Pigs
por: Kamat, Pranitha, et al.
Publicado: (2016)

Characterization of the SARS-CoV-2 co-receptor NRP1 expression profiles in healthy people and cancer patients: Implication for susceptibility to COVID-19 disease and potential therapeutic strategy
por: Huang, Yongbiao, et al.
Publicado: (2022)

Characterization of molecular subtypes based on chromatin regulators and identification of the role of NPAS2 in lung adenocarcinoma
por: Huang, Yongbiao, et al.
Publicado: (2023)

Impact of genetic variant of HIPK2 on the risk of severe radiation pneumonitis in lung cancer patients treated with radiation therapy
por: Tang, Yang, et al.
Publicado: (2020)

Analysis of Ferroptosis-Related LncRNAs Signatures Associated with Tumor Immune Infiltration and Experimental Validation in Clear Cell Renal Cell Carcinoma
por: Chen, Xinyi, et al.
Publicado: (2022)

Dexrazoxane Diminishes Doxorubicin-Induced Acute Ovarian Damage and Preserves Ovarian Function and Fecundity in Mice
por: Kropp, Jenna, et al.
Publicado: (2015)

The Lack of Synergy between Carvedilol and the Preventive Effect of Dexrazoxane in the Model of Chronic Anthracycline-Induced Cardiomyopathy
por: Szponar, Jaroslaw, et al.
Publicado: (2023)

Sitagliptin Alleviates Radiation-Induced Intestinal Injury by Activating NRF2-Antioxidant Axis, Mitigating NLRP3 Inf--lammasome Activation, and Reversing Gut Microbiota Disorder
por: Huang, Shanshan, et al.
Publicado: (2022)

Construction of a Redox-Related Prognostic Model with Predictive Value in Survival and Therapeutic Response for Patients with Lung Adenocarcinoma
por: Xiao, Lingyan, et al.
Publicado: (2022)

A Prognostic Nomogram Model Based on mRNA Expression of DNA Methylation-Driven Genes for Gastric Cancer
por: Chen, Zuhua, et al.
Publicado: (2020)

Pirfenidone facilitates immune infiltration and enhances the antitumor efficacy of PD-L1 blockade in mice
por: Qin, Wan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_l7lj54qq3g2os6ubbb0ubaufhm