LNK promotes granulosa cell apoptosis in PCOS via negatively regulating insulin-stimulated AKT-FOXO3 pathway

Background: Polycystic ovary syndrome (PCOS), which is often accompanied by insulin resistance, is closely related to increased apoptosis of ovarian granulosa cells. LNK is an important regulator of the insulin signaling pathway. When insulin binds to the receptor, the PI3K/AKT/FOXO signaling pathwa...

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Detalles Bibliográficos
Autores principales: Tan, Min, Cheng, Yanxiang, Zhong, Xiaozhu, Yang, Dongyong, Jiang, Sushi, Ye, Yang, Ding, Miao, Guan, Guijun, Yang, Dongzi, Zhao, Xiaomiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906173/
https://www.ncbi.nlm.nih.gov/pubmed/33495419
http://dx.doi.org/10.18632/aging.202421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906173/
https://www.ncbi.nlm.nih.gov/pubmed/33495419
http://dx.doi.org/10.18632/aging.202421

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