ESRP1 regulates alternative splicing of CARM1 to sensitize small cell lung cancer cells to chemotherapy by inhibiting TGF-β/Smad signaling

Epithelial splicing regulatory protein 1 (ESRP1) is an RNA-binding protein that regulates alternative splicing of mRNA. ESRP1 plays an important role in chemoresistance of various cancers, including breast cancer, colon cancer and non-small cell lung cancer. However, the role of ESRP1 and its mechan...

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Detalles Bibliográficos
Autores principales: Zheng, Meng, Niu, Yuchun, Bu, Junguo, Liang, Shumei, Zhang, Zhilin, Liu, Jianhua, Guo, Linlang, Zhang, Zhihua, Wang, Qiongyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906186/
https://www.ncbi.nlm.nih.gov/pubmed/33495408
http://dx.doi.org/10.18632/aging.202295

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