Cargando…

Tumor-associated macrophages promote pancreatic ductal adenocarcinoma progression by inducing epithelial-to-mesenchymal transition

In this study, we investigated the role of tumor-associated macrophages (TAMs) in the progression of pancreatic ductal adenocarcinoma (PDAC). PDAC patients with higher levels of CD68(+) TAMs exhibited shorter overall survival. In Transwell assays, PDAC cells incubated with TAMs or conditioned media...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiong, Cheng, Zhu, Youwei, Xue, Meilin, Jiang, Yongsheng, Zhong, Yiming, Jiang, Lingxi, Shi, Minmin, Chen, Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906203/ https://www.ncbi.nlm.nih.gov/pubmed/33428605 http://dx.doi.org/10.18632/aging.202264

Ejemplares similares

LIPH contributes to glycolytic phenotype in pancreatic ductal adenocarcinoma by activating LPA/LPAR axis and maintaining ALDOA stability
por: Han, Lijie, et al.
Publicado: (2023)

Identification of a novel immune checkpoint molecule V-set immunoglobulin domain-containing 4 that leads to impaired immunity infiltration in pancreatic ductal adenocarcinoma
por: Jiang, Yongsheng, et al.
Publicado: (2023)

Schwann cells regulate tumor cells and cancer-associated fibroblasts in the pancreatic ductal adenocarcinoma microenvironment
por: Xue, Meilin, et al.
Publicado: (2023)

Role of epithelial-mesenchymal transition in chemoresistance in pancreatic ductal adenocarcinoma
por: Hu, Xiu, et al.
Publicado: (2021)

Epithelial to Mesenchymal Transition: Key Regulator of Pancreatic Ductal Adenocarcinoma Progression and Chemoresistance
por: Palamaris, Kostas, et al.
Publicado: (2021)

Oxysterol-Binding Protein 2 Promotes Pancreatic Ductal Adenocarcinoma Progression Through Epithelial-Mesenchymal Transition
por: Huang, Shuai, et al.
Publicado: (2022)

The role of epithelial-mesenchymal transition and autophagy in pancreatic ductal adenocarcinoma invasion
por: Yang, Jian, et al.
Publicado: (2023)

Role of Epithelial-Mesenchymal Transition in Pancreatic Ductal Adenocarcinoma: Is Tumor Budding the Missing Link?
por: Karamitopoulou, Eva
Publicado: (2013)

Clinical Impact of Epithelial-to-Mesenchymal Transition Regulating MicroRNAs in Pancreatic Ductal Adenocarcinoma
por: Dhayat, Sameer Abdallah, et al.
Publicado: (2018)

Inflammation and Epithelial-Mesenchymal Transition in Pancreatic Ductal Adenocarcinoma: Fighting Against Multiple Opponents
por: Khalafalla, Farid G, et al.
Publicado: (2017)

Epithelial to Mesenchymal Transition in Patients with Pancreatic Ductal Adenocarcinoma: State-of-the-Art and Therapeutic Opportunities
por: Dardare, Julie, et al.
Publicado: (2021)

Development and validation of a cancer stem cell-related signature for prognostic prediction in pancreatic ductal adenocarcinoma
por: Feng, Zengyu, et al.
Publicado: (2020)

DDB2 represses epithelial-to-mesenchymal transition and sensitizes pancreatic ductal adenocarcinoma cells to chemotherapy
por: Dardare, Julie, et al.
Publicado: (2022)

Epithelial-to-Mesenchymal Transition in Pancreatic Adenocarcinoma
por: Cano, Carla, et al.
Publicado: (2010)

Cystatin B increases autophagic flux by sustaining proteolytic activity of cathepsin B and fuels glycolysis in pancreatic cancer: CSTB orchestrates autophagy and glycolysis in PDAC
por: Jiang, Yongsheng, et al.
Publicado: (2022)

Snail-Overexpression Induces Epithelial-mesenchymal Transition and Metabolic Reprogramming in Human Pancreatic Ductal Adenocarcinoma and Non-tumorigenic Ductal Cells
por: Liu, Menghan, et al.
Publicado: (2019)

Epithelial-mesenchymal transition induction is associated with augmented glucose uptake and lactate production in pancreatic ductal adenocarcinoma
por: Liu, Menghan, et al.
Publicado: (2016)

Laminin-332 mediates proliferation, apoptosis, invasion, migration and epithelial-to-mesenchymal transition in pancreatic ductal adenocarcinoma
por: Huang, Caiqun, et al.
Publicado: (2021)

Epithelial-to-Mesenchymal Transition in Pancreatic Ductal Adenocarcinoma and Pancreatic Tumor Cell Lines: The Role of Neutrophils and Neutrophil-Derived Elastase
por: Große-Steffen, Thomas, et al.
Publicado: (2012)

Epithelial to mesenchymal plasticity and differential response to therapies in pancreatic ductal adenocarcinoma
por: Porter, Rebecca L., et al.
Publicado: (2019)

Inhibition of DCLK1 kinase reverses epithelial-mesenchymal transition and restores T-cell activity in pancreatic ductal adenocarcinoma
por: Ge, Yang, et al.
Publicado: (2022)

Notch signaling regulates vasculogenic mimicry and promotes cell morphogenesis and the epithelial-to-mesenchymal transition in pancreatic ductal adenocarcinoma
por: Benjakul, Nontawat, et al.
Publicado: (2022)

Endothelial-mesenchymal transition harnesses HSP90α-secreting M2-macrophages to exacerbate pancreatic ductal adenocarcinoma
por: Fan, Chi-Shuan, et al.
Publicado: (2019)

Upregulation of nucleoprotein AHNAK is associated with poor outcome of pancreatic ductal adenocarcinoma prognosis via mediating epithelial-mesenchymal transition
por: Zhang, Zhiwen, et al.
Publicado: (2019)

High expression of both desmoplastic stroma and epithelial to mesenchymal transition markers associate with shorter survival in pancreatic ductal adenocarcinoma
por: Sánchez-Ramírez, Damián, et al.
Publicado: (2022)

PSC-derived Galectin-1 inducing epithelial-mesenchymal transition of pancreatic ductal adenocarcinoma cells by activating the NF-κB pathway
por: Tang, Dong, et al.
Publicado: (2017)

Portal Venous Circulating Tumor Cells Undergoing Epithelial-Mesenchymal Transition Exhibit Distinct Clinical Significance in Pancreatic Ductal Adenocarcinoma
por: Pan, Yujin, et al.
Publicado: (2021)

Correction: PSC-derived Galectin-1 inducing epithelial-mesenchymal transition of pancreatic ductal adenocarcinoma cells by activating the NF-κB pathway
por: Tang, Dong, et al.
Publicado: (2021)

Macrophage-based immunotherapy for the treatment of pancreatic ductal adenocarcinoma
por: Beatty, Gregory L
Publicado: (2013)

The Role of SMAD4 Inactivation in Epithelial–Mesenchymal Plasticity of Pancreatic Ductal Adenocarcinoma: The Missing Link?
por: Racu, Marie-Lucie, et al.
Publicado: (2022)

Epithelial and Mesenchymal Features of Pancreatic Ductal Adenocarcinoma Cell Lines in Two- and Three-Dimensional Cultures
por: Shichi, Yuuki, et al.
Publicado: (2022)

Novel regulatory role of neuropilin-1 in endothelial-to-mesenchymal transition and fibrosis in pancreatic ductal adenocarcinoma
por: Matkar, Pratiek N., et al.
Publicado: (2016)

HSP27 promotes epithelial-mesenchymal transition through activation of the β-catenin/MMP3 pathway in pancreatic ductal adenocarcinoma cells
por: Fang, Zehong, et al.
Publicado: (2019)

Collagen XV Inhibits Epithelial to Mesenchymal Transition in Pancreatic Adenocarcinoma Cells
por: Clementz, Anthony G., et al.
Publicado: (2013)

Conversion of epithelial-to-mesenchymal transition to mesenchymal-to-epithelial transition is mediated by oxygen concentration in pancreatic cancer cells
por: Chen, Shuo, et al.
Publicado: (2018)

Conversion of epithelial-to-mesenchymal transition to mesenchymal-to-epithelial transition is mediated by oxygen concentration in pancreatic cancer cells
por: Chen, Shuo, et al.
Publicado: (2022)

Tumour epithelial vimentin expression and outcome of pancreatic ductal adenocarcinomas
por: Handra-Luca, A, et al.
Publicado: (2011)

Prognostic Biomarkers for Pancreatic Ductal Adenocarcinoma: An Umbrella Review
por: Wang, Yizhi, et al.
Publicado: (2020)

Non-coding RNAs in Pancreatic Ductal Adenocarcinoma
por: Gong, Ruining, et al.
Publicado: (2020)

Luteolin inhibits pancreatitis-induced acinar-ductal metaplasia, proliferation and epithelial-mesenchymal transition of acinar cells
por: Huang, Xince, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_0n7k5he155upfiiqthsmbbblfe