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Overexpression of long noncoding RNA ANRIL inhibits phenotypic switching of vascular smooth muscle cells to prevent atherosclerotic plaque development in vivo

Background: Phenotypic switching of vascular smooth muscle cells (VSMCs) plays a key role in atherosclerosis. Long noncoding RNA ANRIL (lncRNA-ANRIL) is critical in vascular homeostasis. Metformin produces multiple beneficial effects in atherosclerosis. However, the underlying mechanisms need to be...

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Detalles Bibliográficos
Autores principales:	Hu, Da-Jun, Li, Zhen-Yu, Zhu, Yuan-Ting, Li, Chuan-Chang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906209/ https://www.ncbi.nlm.nih.gov/pubmed/33411680 http://dx.doi.org/10.18632/aging.202392

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