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Indole C6 Functionalization of Tryprostatin B Using Prenyltransferase CdpNPT
Tryprostatin A and B are prenylated, tryptophan-containing, diketopiperazine natural products, displaying cytotoxic activity through different mechanisms of action. The presence of the 6-methoxy substituent on the indole moiety of tryprostatin A was shown to be essential for the dual inhibition of t...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906295/ https://www.ncbi.nlm.nih.gov/pubmed/33643664 http://dx.doi.org/10.3390/catal10111247 |