Cargando…

Metabolite profile of Nectandra oppositifolia Nees & Mart. and assessment of antitrypanosomal activity of bioactive compounds through efficiency analyses

EtOH extracts from the leaves and twigs of Nectandra oppositifolia Nees & Mart. shown activity against amastigote forms of Trypanosoma cruzi. These extracts were subjected to successive liquid-liquid partitioning to afford bioactive CH(2)Cl(2) fractions. UHPLC-TOF-HRMS/MS and molecular networkin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alves Conserva, Geanne A., Quirós-Guerrero, Luis M., Costa-Silva, Thais A., Marcourt, Laurence, Pinto, Erika G., Tempone, Andre G., Fernandes, João Paulo S., Wolfender, Jean-Luc, Queiroz, Emerson F., Lago, João Henrique G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906415/ https://www.ncbi.nlm.nih.gov/pubmed/33630860 http://dx.doi.org/10.1371/journal.pone.0247334

Ejemplares similares

Antileishmanial activity and immunomodulatory effect of secosubamolide, a butanolide isolated from Nectandra oppositifolia (Lauraceae)
por: da Costa-Silva, Thais A., et al.
Publicado: (2019)

Crystal structure of Dehydrodieugenol B methyl ether, a neolignan from Nectandra leucantha Nees and Mart (Lauraceae)
por: Grecco, Simone S., et al.
Publicado: (2018)

Discovery of New Hits as Antitrypanosomal Agents by In Silico and In Vitro Assays Using Neolignan-Inspired Natural Products from Nectandra leucantha
por: Araujo, Sheila C., et al.
Publicado: (2021)

Neolignans isolated from twigs of Nectandra leucantha Ness & Mart (Lauraceae) displayed in vitro antileishmanial activity
por: Grecco, Simone S, et al.
Publicado: (2018)

Antitrypanosomal Acetylene Fatty Acid Derivatives from the Seeds of Porcelia macrocarpa (Annonaceae)
por: Santos, Luciana de Á., et al.
Publicado: (2015)

Improving the drug-likeness of inspiring natural products - evaluation of the antiparasitic activity against Trypanosoma cruzi through semi-synthetic and simplified analogues of licarin A
por: Morais, Thiago R., et al.
Publicado: (2020)

Neolignans from Nectandra megapotamica (Lauraceae) Display in vitro Cytotoxic Activity and Induce Apoptosis in Leukemia Cells
por: Ponci, Vitor, et al.
Publicado: (2015)

A New Essential Oil from the Native Andean Species Nectandra laurel Klotzsch ex Nees of Southern Ecuador: Chemical and Enantioselective Analyses
por: Gilardoni, Gianluca, et al.
Publicado: (2023)

Chemical Composition, Antimicrobial Activity, and Antioxidant Activity of Ocotea minarum (Nees & Mart.) Mez.
por: Rodrigues, Allan Belarmino, et al.
Publicado: (2019)

Antileishmanial and antitrypanosomal activity of the cutaneous secretion of Siphonops annulatus
por: Pinto, Erika Gracielle, et al.
Publicado: (2014)

Polyphenolic Composition and Evaluation of Antioxidant Activity, Osmotic Fragility and Cytotoxic Effects of Raphiodon echinus (Nees & Mart.) Schauer
por: Duarte, Antonia Eliene, et al.
Publicado: (2015)

In depth investigation of the metabolism of Nectandra megapotamica chemotypes
por: Farias, Katyuce de S., et al.
Publicado: (2018)

Antimicrobial Activity and Modulatory Effect of Essential Oil from the Leaf of Rhaphiodon echinus (Nees & Mart) Schauer on Some Antimicrobial Drugs
por: Duarte, Antonia Eliene, et al.
Publicado: (2016)

Inventa: A computational tool to discover structural novelty in natural extracts libraries
por: Quiros-Guerrero, Luis-Manuel, et al.
Publicado: (2022)

Evaluating the Antischistosomal Activity of Dehydrodieugenol B and Its Methyl Ether Isolated from Nectandra leucantha—A Preclinical Study against Schistosoma mansoni Infection
por: Rocha, Vinicius C., et al.
Publicado: (2023)

Chiral Separation of Stilbene Dimers Generated by Biotransformation for Absolute Configuration Determination and Antibacterial Evaluation
por: Huber, Robin, et al.
Publicado: (2022)

Metabolomics reveals biomarkers in human urine and plasma to predict cytochrome P450 2D6 (CYP2D6) activity
por: Magliocco, Gaëlle, et al.
Publicado: (2021)

Evaluation of Mollugo oppositifolia Linn. as cholinesterase and β-secretase enzymes inhibitor
por: Das, Bhaskar, et al.
Publicado: (2023)

Marine alkaloids as bioactive agents against protozoal neglected tropical diseases and malaria
por: Tempone, Andre G., et al.
Publicado: (2021)

Characterization of Pseudomonas aeruginosa Quorum Sensing Inhibitors from the Endophyte Lasiodiplodia venezuelensis and Evaluation of Their Antivirulence Effects by Metabolomics
por: Pellissier, Léonie, et al.
Publicado: (2021)

Population genetics of purple saxifrage (Saxifraga oppositifolia) in the high Arctic archipelago of Svalbard
por: Pietiläinen, Maria, et al.
Publicado: (2013)

In Vitro antileishmania activity of sesquiterpene-rich essential oils from Nectandra species
por: Bosquiroli, Lauriane Serpa Silva, et al.
Publicado: (2017)

Influence of Monoterpenes in Biological Activities of Nectandra megapotamica (Spreng.) Mez Essential Oils
por: Danielli, Letícia J., et al.
Publicado: (2019)

On the diversity and richness of understory bryophytes at Nectandra Cloud Forest Reserve, Costa Rica
por: Norris, Daniel H, et al.
Publicado: (2017)

Anti-Neuroinflammatory Potential of a Nectandra angustifolia (Laurel Amarillo) Ethanolic Extract
por: Crescitelli, María Carla, et al.
Publicado: (2023)

Enyne acetogenins from Porcelia macrocarpa displayed anti-Trypanosoma cruzi activity and cause a reduction in the intracellular calcium level
por: Thevenard, Fernanda, et al.
Publicado: (2023)

Antioxidant activities and phenolic contents of the methanol extracts of the stems of Acokanthera oppositifolia and Adenia gummifera
por: Adedapo, Adeolu A, et al.
Publicado: (2008)

New Cytotoxic Seco-Type Triterpene and Labdane-Type Diterpenes from Nuxia oppositifolia
por: Al-Massarani, Shaza M., et al.
Publicado: (2017)

Vaccineren Ja/Nee
por: Loos, Sander
Publicado: (2021)

A taxonomic and molecular survey of the pteridophytes of the Nectandra Cloud Forest Reserve, Costa Rica
por: Nitta, Joel H., et al.
Publicado: (2020)

Isolation, characterization and in vitro cytotoxicity studies of bioactive compounds from Alseodaphne semecarpifolia Nees
por: Chethankumara, Ganadhal Puttaramaiah, et al.
Publicado: (2021)

Phytochemical Composition, Bioactive Compounds, and Antioxidant Properties of Different Parts of Andrographis macrobotrys Nees
por: Dalawai, Dayanand, et al.
Publicado: (2023)

Discovery of Lipid Peroxidation Inhibitors from Bacopa Species Prioritized through Multivariate Data Analysis and Multi-Informative Molecular Networking
por: Saesong, Tongchai, et al.
Publicado: (2019)

A Cytotoxic Porphyrin from North Pacific Brittle Star Ophiura sarsii
por: Klimenko, Antonina, et al.
Publicado: (2020)

Rehenes en marte
por: Cooper, M. G. Cooper, Michael George

Seasonality effects on chemical composition, antibacterial activity and essential oil yield of three species of Nectandra
por: Ferraz, Elza de Oliveira, et al.
Publicado: (2018)

Histone deacetylases as targets for antitrypanosomal drugs
por: Zuma, Aline A, et al.
Publicado: (2018)

Antitrypanosomal butanolides from Aiouea trinervis
por: Nunes, Felipe Oliveira, et al.
Publicado: (2020)

Enantiospecific antitrypanosomal in vitro activity of eflornithine
por: Boberg, Mikael, et al.
Publicado: (2021)

Phosphatidylcholines from Pieris brassicae eggs activate an immune response in Arabidopsis
por: Stahl, Elia, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_o6ntsfcrp2mp3erhj61nu59bpq