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From heterogeneous healthcare data to disease-specific biomarker networks: A hierarchical Bayesian network approach

In this work, we introduce an entirely data-driven and automated approach to reveal disease-associated biomarker and risk factor networks from heterogeneous and high-dimensional healthcare data. Our workflow is based on Bayesian networks, which are a popular tool for analyzing the interplay of bioma...

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Detalles Bibliográficos
Autores principales: Becker, Ann-Kristin, Dörr, Marcus, Felix, Stephan B., Frost, Fabian, Grabe, Hans J., Lerch, Markus M., Nauck, Matthias, Völker, Uwe, Völzke, Henry, Kaderali, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906470/
https://www.ncbi.nlm.nih.gov/pubmed/33577591
http://dx.doi.org/10.1371/journal.pcbi.1008735