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COVID-19-associated pulmonary aspergillosis in a Japanese man: A case report
CAPA (COVID-19 associated pulmonary aspergillosis) is an important complication of COVID-19. It has been reported that the incidence of CAPA is as high as 19%–33% worldwide. However, its onset has not been reported in Japan. A 72-year-old Japanese man was diagnosed with COVID-19 and was transferred...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906536/ https://www.ncbi.nlm.nih.gov/pubmed/33674201 http://dx.doi.org/10.1016/j.jiac.2021.02.026 |
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author | Imoto, Waki Himura, Hoshi Matsuo, Kenji Kawata, Sae Kiritoshi, Ayako Deguchi, Ryo Miyashita, Masahiro Kaga, Shinichiro Noda, Tomohiro Yamamoto, Katsumi Yamada, Koichi Uchida, Kenichiro Nishimura, Tetsuro Yamamoto, Hiromasa Mizobata, Yasumitsu Kakeya, Hiroshi |
author_facet | Imoto, Waki Himura, Hoshi Matsuo, Kenji Kawata, Sae Kiritoshi, Ayako Deguchi, Ryo Miyashita, Masahiro Kaga, Shinichiro Noda, Tomohiro Yamamoto, Katsumi Yamada, Koichi Uchida, Kenichiro Nishimura, Tetsuro Yamamoto, Hiromasa Mizobata, Yasumitsu Kakeya, Hiroshi |
author_sort | Imoto, Waki |
collection | PubMed |
description | CAPA (COVID-19 associated pulmonary aspergillosis) is an important complication of COVID-19. It has been reported that the incidence of CAPA is as high as 19%–33% worldwide. However, its onset has not been reported in Japan. A 72-year-old Japanese man was diagnosed with COVID-19 and was transferred to our hospital due to deterioration of respiratory condition. Treatment with remdesivir, dexamethasone (DEXA), and antibiotics was performed under mechanical ventilation. Although the condition improved temporarily, a new shadow appeared in the lung, and Aspergillus fumigatus was cultured from sputum. The patient was clinically diagnosed with CAPA and treated with voriconazole. However, his progress deteriorated and he died. High-risk COVID-19 patients should be tested for Aspergillus to ensure early diagnosis of CAPA. |
format | Online Article Text |
id | pubmed-7906536 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-79065362021-02-26 COVID-19-associated pulmonary aspergillosis in a Japanese man: A case report Imoto, Waki Himura, Hoshi Matsuo, Kenji Kawata, Sae Kiritoshi, Ayako Deguchi, Ryo Miyashita, Masahiro Kaga, Shinichiro Noda, Tomohiro Yamamoto, Katsumi Yamada, Koichi Uchida, Kenichiro Nishimura, Tetsuro Yamamoto, Hiromasa Mizobata, Yasumitsu Kakeya, Hiroshi J Infect Chemother Case Report CAPA (COVID-19 associated pulmonary aspergillosis) is an important complication of COVID-19. It has been reported that the incidence of CAPA is as high as 19%–33% worldwide. However, its onset has not been reported in Japan. A 72-year-old Japanese man was diagnosed with COVID-19 and was transferred to our hospital due to deterioration of respiratory condition. Treatment with remdesivir, dexamethasone (DEXA), and antibiotics was performed under mechanical ventilation. Although the condition improved temporarily, a new shadow appeared in the lung, and Aspergillus fumigatus was cultured from sputum. The patient was clinically diagnosed with CAPA and treated with voriconazole. However, his progress deteriorated and he died. High-risk COVID-19 patients should be tested for Aspergillus to ensure early diagnosis of CAPA. Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. 2021-06 2021-02-25 /pmc/articles/PMC7906536/ /pubmed/33674201 http://dx.doi.org/10.1016/j.jiac.2021.02.026 Text en © 2021 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Case Report Imoto, Waki Himura, Hoshi Matsuo, Kenji Kawata, Sae Kiritoshi, Ayako Deguchi, Ryo Miyashita, Masahiro Kaga, Shinichiro Noda, Tomohiro Yamamoto, Katsumi Yamada, Koichi Uchida, Kenichiro Nishimura, Tetsuro Yamamoto, Hiromasa Mizobata, Yasumitsu Kakeya, Hiroshi COVID-19-associated pulmonary aspergillosis in a Japanese man: A case report |
title | COVID-19-associated pulmonary aspergillosis in a Japanese man: A case report |
title_full | COVID-19-associated pulmonary aspergillosis in a Japanese man: A case report |
title_fullStr | COVID-19-associated pulmonary aspergillosis in a Japanese man: A case report |
title_full_unstemmed | COVID-19-associated pulmonary aspergillosis in a Japanese man: A case report |
title_short | COVID-19-associated pulmonary aspergillosis in a Japanese man: A case report |
title_sort | covid-19-associated pulmonary aspergillosis in a japanese man: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906536/ https://www.ncbi.nlm.nih.gov/pubmed/33674201 http://dx.doi.org/10.1016/j.jiac.2021.02.026 |
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