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Design, Synthesis, and Biological Activity Studies of Istradefylline Derivatives Based on Adenine as A(2A) Receptor Antagonists

[Image: see text] Due to its double bond, istradefylline rapidly isomerizes to Z-istradefylline when exposed to normal daylight in dilute solution. To solve the poor photostability of the istradefylline solution, a series of istradefylline derivatives (in total 17 compounds, including II-1 and II-2...

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Detalles Bibliográficos
Autores principales:	Wang, Yiyun, Xu, Haojie, Wang, Hongyi, Zheng, Zhonghui, Meng, Zihui, Xu, Zhibin, Li, Jiarong, Xue, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2021
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906590/ https://www.ncbi.nlm.nih.gov/pubmed/33644551 http://dx.doi.org/10.1021/acsomega.0c05741

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