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The potential of rapalogs to enhance resilience against SARS-CoV-2 infection and reduce the severity of COVID-19
COVID-19 disproportionately affects older people, with likelihood of severe complications and death mirroring that of other age-associated diseases. Inhibition of the mechanistic target of rapamycin complex 1 (mTORC1) has been shown to delay or reverse many age-related phenotypes, including declinin...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Author(s). Published by Elsevier Ltd.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906698/ https://www.ncbi.nlm.nih.gov/pubmed/33665645 http://dx.doi.org/10.1016/S2666-7568(20)30068-4 |