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The potential of rapalogs to enhance resilience against SARS-CoV-2 infection and reduce the severity of COVID-19

COVID-19 disproportionately affects older people, with likelihood of severe complications and death mirroring that of other age-associated diseases. Inhibition of the mechanistic target of rapamycin complex 1 (mTORC1) has been shown to delay or reverse many age-related phenotypes, including declinin...

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Detalles Bibliográficos
Autores principales: Bischof, Evelyne, Siow, Richard C, Zhavoronkov, Alex, Kaeberlein, Matt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906698/
https://www.ncbi.nlm.nih.gov/pubmed/33665645
http://dx.doi.org/10.1016/S2666-7568(20)30068-4