Downregulated exosomal microRNA-148b-3p in cancer associated fibroblasts enhance chemosensitivity of bladder cancer cells by downregulating the Wnt/β-catenin pathway and upregulating PTEN

OBJECTIVE: Exosomes derived from cancer-associated fibroblasts (CAFs) are known as important drivers of tumor progression. Previously, microRNA (miR)-148b-3p has been found to be upregulated in bladder cancers as well as in body fluids (blood, urine) of bladder cancer patients. Here, we aimed to exp...

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Detalles Bibliográficos
Autores principales: Shan, Guang, Zhou, Xike, Gu, Juan, Zhou, Daoping, Cheng, Wei, Wu, Huaiguo, Wang, Yueping, Tang, Tian, Wang, Xuedong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906940/
https://www.ncbi.nlm.nih.gov/pubmed/33423167
http://dx.doi.org/10.1007/s13402-020-00500-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906940/
https://www.ncbi.nlm.nih.gov/pubmed/33423167
http://dx.doi.org/10.1007/s13402-020-00500-0

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