BACH2 Enforces the Transcriptional and Epigenetic Programs of Stem-Like CD8(+) T cells

During chronic infection and cancer, a self-renewing CD8(+) T cell subset maintains long-term immunity and is critical to the effectiveness of immunotherapy. These stem-like CD8(+) T cells diverge from other CD8(+) subsets early after chronic viral infection. However, pathways guarding stem-like CD8...

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Detalles Bibliográficos
Autores principales: Yao, Chen, Lou, Guohua, Sun, Hong-Wei, Zhu, Ziang, Sun, Yi, Chen, Zeyu, Chauss, Daniel, Moseman, E. Ashley, Cheng, Jun, D’Antonio, Marc A., Shi, Wangke, Shi, Junwei, Kometani, Kohei, Kurosaki, Tomohiro, Wherry, E. John, Afzali, Behdad, Gattinoni, Luca, Zhu, Yuwen, McGavern, Dorian B., O’Shea, John J., Schwartzberg, Pamela L., Wu, Tuoqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7906956/
https://www.ncbi.nlm.nih.gov/pubmed/33574619
http://dx.doi.org/10.1038/s41590-021-00868-7

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