Effects of FGFR inhibitors TKI258, BGJ398 and AZD4547 on breast cancer cells in 2D, 3D and tissue explant cultures

PURPOSE: Fibroblast growth factor receptors (FGFR) and pathways are important players in breast cancer (BC) development. They are commonly altered, and BCs exhibiting FGFR gene amplification are currently being studied for drug development. Here, we aimed to compare the effects of three FGFR inhibit...

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Detalles Bibliográficos
Autores principales: Kähkönen, T. E., Toriseva, M., Petruk, N., Virta, A.-R., Maher, A., Eigéliené, N., Kaivola, J., Boström, P., Koskivuo, I., Nees, M., Tuomela, J. M., Ivaska, K. K., Härkönen, P. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2020
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907049/
https://www.ncbi.nlm.nih.gov/pubmed/33119860
http://dx.doi.org/10.1007/s13402-020-00562-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907049/
https://www.ncbi.nlm.nih.gov/pubmed/33119860
http://dx.doi.org/10.1007/s13402-020-00562-0

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