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The Putative Role of mTOR Inhibitors in Non-tuberous Sclerosis Complex-Related Epilepsy
Epilepsy affects ~5 out of every 10,000 children per year. Up to one-third of these children have medically refractory epilepsy, with limited to no options for improved seizure control. mTOR, a ubiquitous 289 kDa serine/threonine kinase in the phosphatidylinositol 3-kinase (PI3K)-related kinases (PI...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907183/ https://www.ncbi.nlm.nih.gov/pubmed/33643212 http://dx.doi.org/10.3389/fneur.2021.639319 |