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A quantitative metric for the comparative evaluation of optical clearing protocols for 3D multicellular spheroids

3D multicellular spheroids quickly emerged as in vitro models because they represent the in vivo tumor environment better than standard 2D cell cultures. However, with current microscopy technologies, it is difficult to visualize individual cells in the deeper layers of 3D samples mainly because of...

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Detalles Bibliográficos
Autores principales: Diosdi, Akos, Hirling, Dominik, Kovacs, Maria, Toth, Timea, Harmati, Maria, Koos, Krisztian, Buzas, Krisztina, Piccinini, Filippo, Horvath, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907228/
https://www.ncbi.nlm.nih.gov/pubmed/33717421
http://dx.doi.org/10.1016/j.csbj.2021.01.040