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A quantitative metric for the comparative evaluation of optical clearing protocols for 3D multicellular spheroids
3D multicellular spheroids quickly emerged as in vitro models because they represent the in vivo tumor environment better than standard 2D cell cultures. However, with current microscopy technologies, it is difficult to visualize individual cells in the deeper layers of 3D samples mainly because of...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907228/ https://www.ncbi.nlm.nih.gov/pubmed/33717421 http://dx.doi.org/10.1016/j.csbj.2021.01.040 |