A glycoside analog of mammalian oligomannose formulated with a TLR4-stimulating adjuvant elicits HIV-1 cross-reactive antibodies

The occurrence of oligomannose-specific broadly neutralizing antibodies (bnAbs) has spurred efforts to develop immunogens that can elicit similar antibodies. Here, we report on the antigenicity and immunogenicity of a CRM(197)-conjugate of a previously reported oligomannose mimetic. Oligomannose-spe...

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Detalles Bibliográficos
Autores principales: Bruxelle, Jean-François, Kirilenko, Tess, Trattnig, Nino, Yang, Yiqiu, Cattin, Matteo, Kosma, Paul, Pantophlet, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907241/
https://www.ncbi.nlm.nih.gov/pubmed/33633304
http://dx.doi.org/10.1038/s41598-021-84116-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7907241/
https://www.ncbi.nlm.nih.gov/pubmed/33633304
http://dx.doi.org/10.1038/s41598-021-84116-w

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